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Surface Engineering of Nanomaterials for Biological Application
Inorganic nanoparticles have been attracted due to its unique characteristics. Especially, magnetic nanoparticles have superparamagnetic properties and quantum dots exhibit unique optical properties that are not detected in bulk materials. In order to use these nanoparticles in bio-application,it is necessary to ensure biocompatibility, high stability and provide conjugation site for biomolecules through surface modification.
We have interest in developing and synthesizing newligand designs that responsive to external stimuli and are capable of specific targeting.
1. Design of ligands for bio-compatible nanoparticles
◎ Multidentate polymer for high stability
◎ Control of surface propertiesby using PEG and Zwitterion
◎ Multifunctional for conjugationof targeting agents
◎ Magnetic resonance imaging (MRI) using magnetic nanoparticles
◎ Bioimaging using quantum dots
◎ Cancer theragnosis
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